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A High Prevalence of Post-Covid-19 Fatigue in Patients with Type 2 Diabetes : Study

News Desk, News Nation 360 : Post-COVID-19 syndrome (PCS) or Long COVID has emerged as a major roadblock in the recovery of patients infected with SARS-CoV-2. Amidst many symptoms such as myalgia (muscle pain), headache, cough and breathlessness, fatigue is most prevalent and makes a COVID patient severely debilitated. A recent study conceived by Dr Anoop Misra, Padma Shri, Executive Chairman and Director, Diabetes and Endocrinology, Fortis C-DOC, conducted jointly by Fortis C-DOC, AIIMS, C-NET, N-DOC and Diabetes Foundation and published in the journal, Diabetes & Metabolic Syndrome: Clinical Research & Reviews, reveals that Type 2 diabetes (T2D) patients who had COVID-19 showed significantly more fatigue when compared with patients who did not have COVID-19. The results show that diabetes complicates the course of COVID-19 and results in excess morbidity and mortality, the presence of diabetes also influences PCS via various pathophysiological mechanisms. Further, diabetes poses challenges in the recovery of patients. This is a first of its kind study globally. The methodology followed was to assess patients with T2D who came to the OPD at Fortis CDOC Hospital for Diabetes and Allied Sciences, New Delhi. Patients studied included 52 Type 2 Diabetes patients who had suffered from COVID with mild to moderate severity; 56 Type 2 diabetes patients who did not suffer from COVID. Both groups were matched for age, duration of diabetes, BMI, TSH, serum albumin and vitamin D levels. Matching was done for common factors which may cause fatigue; 25(OH)D, serum albumin and TSH levels. The average time of presentation of patients post-COVID was 92 (range 32-262) days. Symptoms were scored using Chalder Fatigue Scale (reported as fatigue score, FS) and handgrip strength (in kg) was recorded by Jamar Hydraulic Hand Dynamometer. Dr Anoop Misra, Padma Shri, Executive Chairman and Director, Diabetes and Endocrinology, Fortis C-DOC, shared that fatigue is a predominant and very debilitating factor, present afterwards in both hospitalized and non-hospitalized COVID patients. Fatigue and associated symptoms decrease quality of life and interfere with normal working capacity. For the first time, such a collaborative case-control study has been done by Fortis C-DOC, AIIMS, C-NET, N-DOC and Diabetes Foundation and it shows diabetes complicates the course of COVID-19, influences PCS or long COVID via various pathophysiological mechanisms. In addition, diabetes poses challenges in the recovery of patients. It is imperative, therefore, for chronic diabetic patients to follow a healthy lifestyle, adhere to treatment guidelines and go for regular health checks.” The study objective was to assess the prevalence of fatigue using the CFQ-11 and handgrip strength (as a surrogate marker for sarcopenia or muscle mass and power) in patients with Type 2 diabetes after COVID-19 infection and to compare them against patients with diabetes without a history of COVID-19. The sample size assessed was 108 type-2 diabetes patients. 

Report : Anustup Kundu